MAMP Rapid Urine Screening Kits

Download and start MAMP the Mac Apache MySQL PHP distribution version 4.2.1. This tutorial shows you how to install on MAC and where to find the htdocs folde. MAMP Rapid Urine Screening Kits. CE marked Methamphetamine urine screening test kits, also short as MET drug test or mAMP drug test, are one of our rapid drug test kits that are covered by TUV ISO certificate, which can be used as drug self-test devices because of. The finding of MAMP on a urine drug test may have severe consequences for the patient that go beyond health concerns, including potential dismissal from a physician's practice, loss of employment and loss of reputation (4, 8). Thus, correct interpretation of these results is critically important.

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CE marked Methamphetamine urine screening test kits, also short as MET drug test or mAMP drug test, are one of our rapid drug test kits that are covered by TUV ISO13485:2016 certificate, which can be used as drug self-test devices because of the simple testing procedures. The Rapid mAMP tests are a lateral flow chromatographic immunoassay for the detection of Methamphetamine (mAMP or MET in short) in human urine samples at a cut-off concentration value of 1,000ng/mL.

Principle of mAMP Urine Test

MAMP drug rapid test kits are an immunoassay based on the principle of antibody-antigen competitive binding. With mAMP Rapid Test, a Methamphetamine positive urine specimen (mAMP concentration >1,000ng/mL) will not generate a colored line in the test line region because drug methamphetamine and its metabolites have taken all the binding sites at the test region, leaving no binding sites for the colloidal gold particles. While with a mAMP-negative urine specimen or a specimen containing a drug concentration less than the cut-off number, the colloidal gold particle will be captured at the testing line region, the accumulation of these color particle will generate a pink or purple line in the testing line region, indicating a negative result.

In short, with methamphetamine rapid Tests, two lines indicate a negative result, and only one pink line at control region indicates a positive result. If there are no line appears at all, this means the test reagents have deteriorated, or some mistake happens during the testing procedure. Repeat the assay with a new mAMP test strip or mAMP test cassette.

Merits of the MET Urine Test strip and Cassette:

• MAMP immunoassay tests are highly sensitive and specific;
• MET test devices results are read visually without the need for other instrumentation or any extra chemical reagent;
• mAMP Urine test devices are intended for IVD use only;
• One-Step mAMP tests are available in both strip and cassette styles, and also is one parameter of Multi drug test panels;
• Our rapid Methamphetamine tests are CE marked products.

MET Drug Abuse Urine Screening Kits

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Methamphetamine is an addictive stimulant drug that strongly activates certain systems in the brain. Methamphetamine is chemically related to amphetamine, but the central nervous system effects of methamphetamine are greater. Both drugs have some limited therapeutic uses, primarily in the treatment of obesity.

Methamphetamine is made in illegal laboratories and has a high potential for abuse and addiction. Street methamphetamine is referred to by many names, such as “speed,” “meth,” and “chalk.” Methamphetamine hydrochloride, clear chunky crystals resembling ice, which can be inhaled by smoking, is referred to as “ice,” “crystal,” “glass,” and “tina.”

Health Hazards

Methamphetamine releases high levels of the neurotransmitter dopamine, which stimulates brain cells, enhancing mood and body movement. It also appears to have a neurotoxic effect, damaging brain cells that contain dopamine as well as serotonin, another neurotransmitter. Over time, methamphetamine appears to cause reduced levels of dopamine, which can result in symptoms like those of Parkinson’s disease, a severe movement disorder.

Methamphetamine is taken orally or intranasally (snorting the powder), by intravenous injection, and by smoking. Immediately after smoking or intravenous injection, the methamphetamine user experiences an intense sensation, called a “rush” or “flash,” that lasts only a few minutes and is described as extremely pleasurable. Oral or intranasal use produces euphoria—a high, but not a rush. Users may become addicted quickly, and use it with increasing frequency and in increasing doses.

Animal research going back more than 20 years shows that high doses of methamphetamine damage neuron cell endings. Dopamine- and serotonin-containing neurons do not die after methamphetamine use, but their nerve endings (“terminals”) are cut back, and regrowth appears to be limited.

The central nervous system (CNS) actions that result from taking even small amounts of methamphetamine include increased wakefulness, increased physical activity, decreased appetite, increased respiration, hyperthermia, and euphoria. Other CNS effects include irritability, insomnia, confusion, tremors, convulsions, anxiety, paranoia, and aggressiveness. Hyperthermia and convulsions can result in death.

Methamphetamine causes increased heart rate and blood pressure and can cause irreversible damage to blood vessels in the brain, producing strokes. Other effects of methamphetamine include respiratory problems, irregular heartbeat, and extreme anorexia. Its use can result in cardiovascular collapse and death.

Extent of Use

Monitoring the Future Study (MTF)*
MTF assesses the extent of drug use among adolescents (8th-, 10th-, and 12th-graders) and young adults across the country. Recent data from the survey indicate the following:

• In 2004, 6.2 percent of high school seniors had reported lifetime** use of methamphetamine, statistically unchanged from 2003. Lifetime use was measured at 5.3 percent of 10th grade students.
• Eighth-graders reported significant decreases in lifetime, annual, and 30-day use.

Community Epidemiology Work Group (CEWG)**
Results reported at the most recent CEWG meetings indicate that methamphetamine abuse and production continue at high levels in Hawaii, west coast areas, and some southwestern areas of the United States—but methamphetamine abuse also is continuing to spread eastward.

The percentage of adult male arrestees testing methamphetamine-positive in 2003 were highest in Honolulu (40.3 percent), Phoenix (38.3) San Diego (36.2), and Los Angeles (28.7).

Several other items of significance were reported, as follows:

Mampuestos

• The numbers of clandestine methamphetamine laboratory incidents reported to the National Clandestine Laboratory Database decreased from 1999 to 2004. During this same period, methamphetamine lab incidents increased in midwestern States (Illinois, Michigan, and Ohio), and in Pennsylvania. In 2004, more lab incidents were reported in Illinois (926) than in California (673). In 2003, methamphetamine lab incidents reached new highs in Georgia (250), Minnesota (309), and Texas (677). There were only seven methamphetamine lab incidents reported in Hawaii in 2004.
• In the first 6 months of 2004, nearly 59 percent of substance abuse treatment admissions (excluding alcohol) in Hawaii were for primary methamphetamine abuse. San Diego followed, with nearly 51 percent. Notable increases in methamphetamine treatment admissions occurred in Atlanta (10.6 percent in the first 6 months of 2004, as compared with 2.5 percent in 2001) and Minneapolis/St. Paul (18.7 percent in the first 6 months of 2004, as compared with 10.6 percent in 2001).
• Some MDMA (ecstasy) and cocaine users are switching to methamphetamine, ignorant of its severe toxicity.
• In many gay clubs found throughout New York City and elsewhere, methamphetamine is often used in an injectable form, placing users and their partners at risk for transmission of HIV, hepatitis C, and other STDs.

What is Crystal Meth?
Crystal Methamphetamine, better known as crystal meth, comes in many forms and can be smoked, snorted, orally ingested, or injected. The drug alters moods in different ways, depending on how it is taken. Immediately after smoking the drug or injecting it intravenously, the user experiences an intense rush or “flash” that lasts only a few minutes and is described as extremely pleasurable. Snorting or oral ingestion produces euphoria – a high but not an intense rush. Snorting produces effects within 3 to 5 minutes, and oral ingestion produces effects within 15 to 20 minutes. As with similar stimulants, methamphetamine most often is used in a “binge and crash” pattern. Because tolerance for methamphetamine occurs within minutes – meaning that the pleasurable effects disappear even before the drug concentration in the blood falls significantly – users try to maintain the high by binging on the drug. In the 1980’s, “ice,” a smokable form of methamphetamine, came into use. Ice is a large, usually clear crystal of high purity that is smoked in a glass pipe like crack cocaine. The smoke is odorless, leaves a residue that can be smoked, and produces effects that may continue for 12 hours or more.

As a powerful stimulant, methamphetamine, even in small doses, can increase wakefulness and physical activity and decrease appetite. A brief, intense sensation, or rush, is reported by those who smoke or inject methamphetamine. Oral ingestion or snorting produces a long-lasting high instead of a rush, which reportedly can continue for as long as half a day. Both the rush and the high are believed to result from the release of very high levels of the neurotransmitter dopamine into areas of the brain that regulate feelings of pleasure.

Long-term methamphetamine abuse results in many damaging effects, including addiction. Addiction is a chronic, relapsing disease, characterized by compulsive drug-seeking and drug use which is accompanied by functional and molecular changes in the brain. In addition to being addicted to methamphetamine, chronic methamphetamine abusers exhibit symptoms that can include violent behavior, anxiety, confusion, and insomnia. They also can display a number of psychotic features, including paranoia, auditory hallucinations, mood disturbances, and the paranoia can result in homicidal as well as suicidal thoughts.

False Positive For Mamp

With chronic use, tolerance for methamphetamine can develop. In an effort to intensify the desired effects, users may take higher doses of the drug, take it more frequently, or change their method of drug intake. In some cases, abusers forego food and sleep while indulging in a form of binging known as a “run,” injecting as much as a gram of the drug every 2 to 3 hours over several days until the user runs out of the drug or is too disorganized to continue. Chronic abuse can lead to psychotic behavior, characterized by intense paranoia, visual and auditory hallucinations, and out-of-control rages that can be coupled with extremely violent behavior.
Source: Parts reprinted from The National Institute on Drug Abuse (NIDA)